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How to Choose the Right Pipette Tip?

Before selecting a pipette, you must understand how to choose the right tip for it. This tip will determine the accuracy and precision of the measurements that you make. Cheap and poor-quality tips can lead to batch-to-batch variations, which may compromise the accuracy of your experiment. Choose high-quality tips from a reputable company to ensure that there is minimal variability between tips. Using an incorrectly fitted tip can also affect the accuracy of the results.

Precision Tips

LTS Pipette Tips are only as good as the tip you use. Precision tips can improve the quality of the results, save time and reduce the risk of contamination. You should always choose the tip based on your application. This guide will help you select the tip that will meet your needs best. Listed below are some tips for different pipettes. They are:–

  • The first thing to keep in mind is the volume of the sample you need to pipette.
  • The smaller the volume of the sample, the better. If you are only planning on using a small volume of a sample, a pipette that can handle 50 ml is ideal.
  • The next tip to consider is the size. If you are using a standard pipette, you can try a universal tip, but it may cause a leak, loosening or stretching of the tip rim.

Universal Tips

Universal tips fit most micropipettes. They also fit all pipette barrels, which may vary slightly from manufacturer to manufacturer. These universal tips may have a slightly different radius than your pipette’s barrel. If these are not available, try using a universal tip. Ultimately, this way, you can use the same pipette without worrying about fit issues. The versatility of a universal tip is a big benefit when you’re performing research on multiple samples.

Compatibility Chart

If you buy a new pipette, you’ll want to make sure it is compatible with your pipettor. Ensure that the tip fits snugly without being forced. Most companies have compatibility charts to help you with this decision. When purchasing a new pipette tip, you should first check the compatibility chart of the tip with the pipettor you’re using. This is crucial when it comes to choosing the right tip.

Shape & Quality of Pipette Tip

The shape and quality of the pipette tip is an important factor when choosing one. Choosing the wrong tip may affect accuracy or precision. Incorrect fit can lead to air escaping from the pipette barrel. This may reduce the amount of liquid that is aspirated or dispensed. To make sure your pipette tip is the best for your application, make sure it is accurate and cadmium-free.

While you may be working with a liquid that is highly viscous, consider using a low-retention tip to reduce the risk of cross contamination. Low-retention tips are perfect for preparing samples in a laboratory environment that demands high reproducibility and accuracy. For these types of liquids, you may have to dispose of some of the liquid that is left in the pipette after dispensing. Low-retention tips have hydrophobic plastic additives to keep liquids from sticking to the tip.

Two Types of Tips

There are two types of tips: barrier and non-barrier. Barrier tips are designed for use with non-hazardous chemicals, while non-barrier tips are made for use with hazardous chemicals. Choosing the right tip for your application is essential, so make sure to research the different types of pipettes. You’ll be glad you did. You can be sure that you’re getting the best tip for the job!

Sterile & Free of Endotoxins

A certified tip must be sterile and free of endotoxins. Some tips are autoclavable. Make sure to check the sterilization certificate before purchasing. You should also check for the RNase, DNA, and bile salts content of the pipette tip. If you’re working with sensitive assays, you should make sure that your pipette tip is sterile and RNase-free. If you’re worried about contamination, you can purchase tips in bulk to save money on the cost.

Blood Test & Research Study

A small, inexpensive tool, the Pipette Tip powers every blood test and research study. Bench scientists may use dozens of these tips in a single day. But there are many reasons why they are so important to science. Blackouts, pandemics, and other factors are putting pressure on the supply chain. And while the White House says it is working to increase pipette tip supplies, the shortage has not been alleviated.

Last Words:

A poor fit between the tip and the pipette can greatly impact the accuracy of your results. A bad seal can allow air to escape from the pipette barrel, resulting in an inaccurate volume of liquid being aspirated. Choose your pipette tips carefully. Some manufacturers sell replacement tips for their pipettes, but the best bet is usually a high-quality universal tip. Here’s how to choose a pipette tip that fits your pipettes:

 

 

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